Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mip  major intrinsic protein of lens fiber   (Synonyms: Aqp0, aquaporin 0, Cts, lens opacity, Lop, MIP26, shrivelled, Svl)
Results	Reference
1	J:30314 Chow RL, Roux GD, Roghani M, Palmer MA, Rifkin DB, Moscatelli DA, Lang RA, FGF suppresses apoptosis and induces differentiation of fibre cells in the mouse lens. Development. 1995 Dec;121(12):4383-93
1*	J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27
1*	J:104492 Huang KM, Wu J, Duncan MK, Moy C, Dutra A, Favor J, Da T, Stambolian D, Xcat, a novel mouse model for Nance-Horan syndrome inhibits expression of the cytoplasmic-targeted Nhs1 isoform. Hum Mol Genet. 2006 Jan 15;15(2):319-27
1	J:312372 Karnam S, Maddala R, Stiber JA, Rao PV, Drebrin, an actin-binding protein, is required for lens morphogenesis and growth. Dev Dyn. 2021 Nov;250(11):1600-1617
1	J:257373 Logan CM, Bowen CJ, Menko AS, Induction of Immune Surveillance of the Dysmorphogenic Lens. Sci Rep. 2017 Nov 24;7(1):16235
1	J:175548 Maddala R, Skiba NP, Lalane R 3rd, Sherman DL, Brophy PJ, Rao PV, Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers. Dev Biol. 2011 Sep 1;357(1):179-90
1	J:326946 Martin JB, Herman K, Houssin NS, Rich W, Reilly MA, Plageman TF Jr, Arvcf Dependent Adherens Junction Stability is Required to Prevent Age-Related Cortical Cataracts. Front Cell Dev Biol. 2022;10:840129
1*	J:276637 Matsuyama M, Tanaka H, Inoko A, Goto H, Yonemura S, Kobori K, Hayashi Y, Kondo E, Itohara S, Izawa I, Inagaki M, Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells. J Biol Chem. 2013 Dec 13;288(50):35626-35
1*	J:345818 Petrova RS, Francis N, Schey KL, Donaldson PJ, Verification of the gene and protein expression of the aquaglyceroporin AQP3 in the mammalian lens. Exp Eye Res. 2024 Mar;240:109828
1	J:230267 Petrova RS, Schey KL, Donaldson PJ, Grey AC, Spatial distributions of AQP5 and AQP0 in embryonic and postnatal mouse lens development. Exp Eye Res. 2015 Mar;132:124-35
1	J:270142 Rasiah PK, Maddala R, Bennett V, Rao PV, Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth. Dev Biol. 2019 Feb 1;446(1):119-131
1	J:151538 Rivera C, Yamben IF, Shatadal S, Waldof M, Robinson ML, Griep AE, Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis. Dev Dyn. 2009 Jul 21;238(9):2292-2308
1	J:1539 Shiels A, Griffin CS, Muggleton-Harris AL, Immunochemical comparison of the major intrinsic protein of eye-lens fibre cell membranes in mice with hereditary cataracts. Biochim Biophys Acta. 1991 Nov 21;1097(4):318-24
1	J:195994 Son AI, Cooper MA, Sheleg M, Sun Y, Kleiman NJ, Zhou R, Further analysis of the lens of ephrin-A5-/- mice: development of postnatal defects. Mol Vis. 2013;19:254-66
1	J:237527 Thein T, de Melo J, Zibetti C, Clark BS, Juarez F, Blackshaw S, Control of lens development by Lhx2-regulated neuroretinal FGFs. Development. 2016 Nov 01;143(21):3994-4002
1*	J:120884 Varadaraj K, Kumari SS, Mathias RT, Functional expression of aquaporins in embryonic, postnatal, and adult mouse lenses. Dev Dyn. 2007 May;236(5):1319-28
1	J:270322 Wada K, Saito J, Yamaguchi M, Seki Y, Furugori M, Takahashi G, Nishito Y, Matsuda H, Shitara H, Kikkawa Y, Pde6b(rd1) mutation modifies cataractogenesis in Foxe3(rct) mice. Biochem Biophys Res Commun. 2018 Jan 29;496(1):231-237
1	J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922
1	J:76265 West-Mays JA, Coyle BM, Piatigorsky J, Papagiotas S, Libby D, Ectopic expression of AP-2alpha transcription factor in the lens disrupts fiber cell differentiation. Dev Biol. 2002 May 1;245(1):13-27
1	J:52402 West-Mays JA, Zhang J, Nottoli T, Hagopian-Donaldson S, Libby D, Strissel KJ, Williams T, AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle. Dev Biol. 1999 Feb 1;206(1):46-62
1	J:174241 Wiley LA, Rajagopal R, Dattilo LK, Beebe DC, The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens. Dis Model Mech. 2011 Jul-Aug;4(4):484-95
1*	J:282278 Zhou Y, Bennett TM, Shiels A, A charged multivesicular body protein (CHMP4B) is required for lens growth and differentiation. Differentiation. 2019 Sep - Oct;109:16-27